Transgenesis and Targeted Mutagenesis in Immunology

Investigations into the field of immunology are rapidly expanding with the use of genetically altered mice at the embryonic stage. This breakthrough laboratory guide provides a complete study of transgenesis and targeted mutagenesis in laboratory mice that will be valued by researchers looking for fresh observations and interpretations when designing future experiments.
Special Features Include:
Contributions of two Nobel Prize winners
Addresses the use of mouse models in studying the immune system
Targets gene distribution in embryonic stem cells and their introduction into blastocyte mice models
Analyzes the in vivo functional loss of embryonic cells
A practical, useful guidebook for individual researchers, laboratories, and libraries